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Neurotrimin

From Wikipedia, the free encyclopedia
NTM
Identifiers
AliasesNTM, HNT, IGLON2, NTRI, neurotrimin, CEPU-1
External IDsOMIM: 607938; MGI: 2446259; HomoloGene: 41139; GeneCards: NTM; OMA:NTM - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 11: 131.37 – 132.34 MbChr 9: 28.91 – 29.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neurotrimin is a protein that in humans is encoded by the NTM gene.[5][6]

This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML) on chromosome 11. Multiple alternatively spliced variants have been found but only two variants have had their full-length sequences determined.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000182667Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059974Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Struyk AF, Canoll PD, Wolfgang MJ, Rosen CL, D'Eustachio P, Salzer JL (Apr 1995). "Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules". J Neurosci. 15 (3 Pt 2): 2141–56. doi:10.1523/JNEUROSCI.15-03-02141.1995. PMC 6578143. PMID 7891157.
  6. ^ a b "Entrez Gene: HNT neurotrimin".

Further reading

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