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Flosequinan

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Flosequinan
Clinical data
ATC code
Identifiers
  • 7-fluoro-3-methanesulfinyl-1-methyl-1,4-dihydroquinolin-4-one
CAS Number
PubChem CID
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H10FNO2S
Molar mass239.267 g/mol g·mol−1

Flosequinan is a quinolone vasodilator. It has direct relaxing effects on peripheral arteries and veins. It is administered orally in cases of congestive heart failure in patients who are not responsive to digitalis or ACE inhibitors. It was sold under the trade name Manoplax.

It was withdrawn from the US market in October 1993 due to an increased risk of hospitalization or death.[1]

References

  1. ^ "Heart drug withdrawn - Boots Pharmaceuticals' Manoplax". FDA Consumer. 1993. Retrieved 2008-12-01.