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SSRI?

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http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4c55ccfb-c4cf-11df-851a-0800200c9a66#section-11

"VIIBRYD Tablets for oral administration contain polymorph Form IV vilazodone hydrochloride (HCl), a selective serotonin reuptake inhibitor and a 5HT1A receptor partial agonist."

Is it really an SSRI? If yes, please add to article.--4h8s (talk) 14:58, 3 October 2013 (UTC)[reply]

It’s another class technically. Think of it as ssri 2.0. Most the new drugs hit SERT then also try and hit 5-HT1A and maybe a few others to get a favorable effect profile. Technically a SERM serotonin receptor modulator. Eg it has multiple effects in the serotonin system - and likely other monoamine systems. Dopamine norepinephrine epinephrine (adrenergic alpha, beta) etc Gizmo.AT (talk) 04:08, 31 August 2020 (UTC)[reply]

To clarify - anything that has a low number next to “SERT” in the pharmacokinetics section is technically an SSRI in the “lay” parlance. E.g it has a significant effect at the reuptake transporter Gizmo.AT (talk) 04:11, 31 August 2020 (UTC)[reply]

Clinically insignificant effects at the NET receptor

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Yea freaking right. Skim the side effects and effects, and the NET activity (or downstream effects) are rather important here. Speaking from experience here. Was a bit surprised at how activating and sympathomimetic this was. Not in a good way. D/c’d after a month or two of sweaty diarrhea. Gizmo.AT (talk) 04:04, 31 August 2020 (UTC)[reply]