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AMY2B

From Wikipedia, the free encyclopedia
AMY2B
Identifiers
AliasesAMY2B, AMY2, AMY3, HXA, amylase, alpha 2B (pancreatic), amylase alpha 2B (pancreatic), amylase alpha 2B
External IDsOMIM: 104660; MGI: 3714985; HomoloGene: 134663; GeneCards: AMY2B; OMA:AMY2B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020978
NM_001386109
NM_001387437

NM_001160151

RefSeq (protein)

NP_066188

NP_001036176
NP_001153622
NP_001153623
NP_001153624

Location (UCSC)Chr 1: 103.55 – 103.58 MbChr 3: 113.22 – 113.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene.[5][6]

Function

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Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside] bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000240038Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000093931Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Omichi K, Hase S (December 1993). "Identification of the characteristic amino-acid sequence for human alpha-amylase encoded by the AMY2B gene". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1203 (2): 224–9. doi:10.1016/0167-4838(93)90087-8. PMID 8268204.
  6. ^ a b "Entrez Gene: AMY2B amylase, alpha 2B (pancreatic)".
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Further reading

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