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CCNI (gene)

From Wikipedia, the free encyclopedia
CCNI
Identifiers
AliasesCCNI, CCNI1, CYC1, CYI, cyclin I
External IDsMGI: 1341077; HomoloGene: 4979; GeneCards: CCNI; OMA:CCNI - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006835

NM_017367

RefSeq (protein)

NP_059063

Location (UCSC)n/aChr 5: 93.33 – 93.35 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Cyclin-I is a protein that in humans is encoded by the CCNI gene.[4][5]

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.[5]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063015Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Nakamura T, Sanokawa R, Sasaki YF, Ayusawa D, Oishi M, Mori N (Jan 1996). "Cyclin I: a new cyclin encoded by a gene isolated from human brain". Exp Cell Res. 221 (2): 534–42. doi:10.1006/excr.1995.1406. PMID 7493655.
  5. ^ a b "Entrez Gene: CCNI cyclin I".
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Further reading

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