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Integrator complex subunit 5

From Wikipedia, the free encyclopedia
INTS5
Identifiers
AliasesINTS5, INT5, KIAA1698, integrator complex subunit 5
External IDsOMIM: 611349; MGI: 1923578; HomoloGene: 35303; GeneCards: INTS5; OMA:INTS5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030628

NM_176843

RefSeq (protein)

NP_085131

NP_789813

Location (UCSC)Chr 11: 62.65 – 62.65 MbChr 19: 8.87 – 8.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Integrator complex subunit 5 is a protein that in humans is encoded by the INTS5 gene. [5]

Function

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The Integrator complex is a complex that associates with the C-terminal domain of RNA polymerase II large subunit. This complex is brought to U1 and U2 small nuclear RNA genes, where it is involved in the transcription and processing of their transcripts. The protein encoded by this gene represents a subunit of the Integrator complex.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185085Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000071652Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Integrator complex subunit 5". Retrieved 2017-10-09.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.