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KIFC1

From Wikipedia, the free encyclopedia
KIFC1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIFC1, HSET, KNSL2, kinesin family member C1
External IDsOMIM: 603763; MGI: 2137414; HomoloGene: 83229; GeneCards: KIFC1; OMA:KIFC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002263

NM_016761
NM_053173

RefSeq (protein)

NP_002254

NP_001182227

Location (UCSC)Chr 6: 33.39 – 33.41 MbChr 17: 27.14 – 27.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.[5][6]

Function

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The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References

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  1. ^ a b c ENSG00000204197, ENSG00000237649, ENSG00000056678 GRCh38: Ensembl release 89: ENSG00000233450, ENSG00000204197, ENSG00000237649, ENSG00000056678Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024301Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466. S2CID 8880453.
  6. ^ "Entrez Gene: KIFC1 kinesin family member C1".

Further reading

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  • Overview of all the structural information available in the PDB for UniProt: Q9BW19 (Human Kinesin-like protein KIFC1) at the PDBe-KB.