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PLA2G4E (gene)

From Wikipedia, the free encyclopedia
PLA2G4E
Identifiers
AliasesPLA2G4E, phospholipase A2 group IVE
External IDsMGI: 1919144; HomoloGene: 65339; GeneCards: PLA2G4E; OMA:PLA2G4E - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001080490
NM_001206670
NM_001395548
NM_198442

NM_177845
NM_001363090
NM_001363091
NM_001395470

RefSeq (protein)

NP_001193599

NP_808513
NP_001350019
NP_001350020
NP_001382399

Location (UCSC)Chr 15: 41.98 – 42.05 MbChr 2: 120 – 120.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phospholipase A2 group IVE is a protein that in humans is encoded by the PLA2G4E gene. [5]

Function

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This gene encodes a member of the cytosolic phospholipase A2 group IV family. Members of this family are involved in regulation of membrane tubule-mediated transport. The enzyme encoded by this member of the family plays a role in trafficking through the clathrin-independent endocytic pathway. The enzyme regulates the recycling process via formation of tubules that transport internalized clathrin-independent cargo proteins back to the cell surface. [provided by RefSeq, Jan 2017].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188089Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050211Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Phospholipase A2 group IVE". Retrieved 2018-06-13.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.