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Streptothricin hydrolase

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Streptothricin hydrolase
Identifiers
EC no.3.5.2.19
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Streptothricin hydrolase (EC 3.5.2.19, sttH (gene)) is an enzyme with systematic name streptothricin-F hydrolase.[1][2] This enzyme catalyses the following chemical reaction

streptothricin-F + H2O streptothricin-F acid

The enzyme also catalyses the hydrolysis of streptothricin-D to streptothricin-D acid.

References

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  1. ^ Maruyama C, Hamano Y (November 2009). "The biological function of the bacterial isochorismatase-like hydrolase SttH". Bioscience, Biotechnology, and Biochemistry. 73 (11): 2494–500. doi:10.1271/bbb.90499. PMID 19897889.
  2. ^ Hamano Y, Matsuura N, Kitamura M, Takagi H (June 2006). "A novel enzyme conferring streptothricin resistance alters the toxicity of streptothricin D from broad-spectrum to bacteria-specific". The Journal of Biological Chemistry. 281 (25): 16842–8. doi:10.1074/jbc.m602294200. PMID 16641084.
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