User contributions for SpaceShepherd
A user with 6 edits. Account created on 14 April 2023.
31 August 2023
- 22:2322:23, 31 August 2023 diff hist −114 Marilyn Kozak Updated to better reflect the current state of the science surrounding cellular IRESes. Removed a sentence supported only by a poorly sourced, seemingly agenda-driven blogpost.
- 22:0422:04, 31 August 2023 diff hist +967 Marilyn Kozak Undid revision 1173196250 by SpaceShepherd (talk) Edit published by mistake Tag: Undo
- 22:0222:02, 31 August 2023 diff hist −967 Marilyn Kozak Removed a sentence supporting doubts expressed by the article subject about the existence of IRES sequences. The referenced article was from 2006 and the controversy has since been settled in the opposite direction. Tags: Reverted references removed
14 April 2023
- 04:1604:16, 14 April 2023 diff hist +83 Chimeric small molecule therapeutics No edit summary
- 04:1204:12, 14 April 2023 diff hist +409 Chimeric small molecule therapeutics No edit summary
- 03:5203:52, 14 April 2023 diff hist +20,918 N Chimeric small molecule therapeutics ←Created page with '{{subst:submit}} '''Chimeric small molecule therapeutics''' Chimeric small molecule therapeutics are a class of drugs designed with multiple active domains to operate outside of the typical protein inhibition model. While most small molecule drugs inhibit target proteins by binding their active site, chimerics form protein-protein ternary structures to induce degradation or, less frequently, other protein modifications. '''Background''' Small molecule d...'
