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SEMA6A

From Wikipedia, the free encyclopedia
SEMA6A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSEMA6A, HT018, SEMA, SEMA6A1, SEMAQ, VIA, semaphorin 6A
External IDsOMIM: 605885; MGI: 1203727; HomoloGene: 32426; GeneCards: SEMA6A; OMA:SEMA6A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300780
NM_020681
NM_020796

NM_018744
NM_001311097

RefSeq (protein)

NP_001287709
NP_065847

NP_001298026
NP_061214

Location (UCSC)Chr 5: 116.44 – 116.57 MbChr 18: 47.37 – 47.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Semaphorin-6A is a protein that in humans is encoded by the SEMA6A gene.[5][6][7]

In melanocytic cells SEMA6A gene expression may be regulated by MITF.[8]


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000092421Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019647Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhou L, White FA, Lentz SI, Wright DE, Fisher DA, Snider WD (Sep 1997). "Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I". Mol Cell Neurosci. 9 (1): 26–41. doi:10.1006/mcne.1997.0607. PMID 9204478. S2CID 38730386.
  6. ^ Klostermann A, Lutz B, Gertler F, Behl C (Jan 2001). "The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain". J Biol Chem. 275 (50): 39647–53. doi:10.1074/jbc.M006316200. PMID 10993894.
  7. ^ "Entrez Gene: SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A".
  8. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. S2CID 24698373.

Further reading

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