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Talk:Mitsunobu reaction

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Mitsunobu_reaction_Application.png

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The reaction scheme at the bottom showing a phenolic nucleophile has an obvious error. On the reactant side the phenolic nucleophile has a pyridyl nitrogen meta to it, while on the product side it does not. —Preceding unsigned comment added by 8.21.180.41 (talk) 23:28, 6 December 2010 (UTC)[reply]

Fixed. -- Ed (Edgar181) 18:32, 14 July 2011 (UTC)[reply]

Reaction mechanism

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There seems to be a mistake in the reaction mechanism (2nd step): The nitrogen lacks a free electron pair. Ir should be negatively charged, while the phosphorous is positively charged. Or am I mistaken? 92.74.204.235 (talk) 17:57, 14 July 2011 (UTC)[reply]

It would be nice to show the lone pair on nitrogen, for clarity. But I wouldn't consider it wrong not to have it. -- Ed (Edgar181) 18:32, 14 July 2011 (UTC)[reply]

Ylide?

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"This white, cloudy suspension is the ylide." Should this not say betaine instead? Ylides are molecules with atoms of opposing formal charge connected to each other. This shouldn't be an ylide then, what is formed is the betaine, where there's another nitrogen between the negatively charged nitrogen and PPh3+. Maybe this is just a convention to call it an ylide anyway? Natriumcyanid (talk) 09:28, 24 January 2023 (UTC)[reply]