Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment (Q60950062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

2 references

20 November 2020

18 July 2021

Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

2 references

20 November 2020

1 reference

2 references

18 July 2021

1 reference

human digestive system

1 reference

7 October 2019

1 reference

12 October 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Isabelle A Leclercq

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Laure-Alix Clerbaux

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Rita Manco

1

0 references

Isabelle A. Leclercq

2

0 references

language of work or name

English

0 references

publication date

18 December 2018

6 references

20 June 2019

7 October 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

20 November 2020

18 July 2021

December 2018

0 references

full work available at URL

https://www.mdpi.com/1422-0067/19/12/4115

0 references

published in

International Journal of Molecular Sciences

6 references

20 June 2019

7 October 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

20 November 2020

18 July 2021

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

15 April 2020

page(s)

4115

0 references

copyright license

5 references

20 June 2019

7 October 2019

12 October 2019

20 November 2020

18 July 2021

0 references

Kinetics of hepatocellular proliferation after partial resection of the liver

1 reference

12 December 2020

An autoradiographic study of the 3H-uridine and 3H-thymidine incorporation in the regenerating mouse liver

1 reference

12 December 2020

The liver as a stem cell and lineage system

1 reference

12 December 2020

Inhibitory effect of transforming growth factor-beta on DNA synthesis of adult rat hepatocytes in primary culture

1 reference

12 December 2020

1 reference

12 December 2020

Messenger RNA in regenerating liver: implications for the understanding of regulated growth

1 reference

12 December 2020

Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation

1 reference

12 December 2020

Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors

1 reference

12 December 2020

Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver

1 reference

12 December 2020

Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium

1 reference

12 December 2020

Liver regeneration 4: transcriptional control of liver regeneration.

1 reference

12 December 2020

Zonation of parenchymal and nonparenchymal metabolism in liver

1 reference

12 December 2020

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

12 December 2020

Isolation of oval cells from Long-Evans Cinnamon rats and their transformation into hepatocytes in vivo in the rat liver

1 reference

12 December 2020

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

1 reference

12 December 2020

Deficient liver regeneration after carbon tetrachloride injury in mice lacking type 1 but not type 2 tumor necrosis factor receptor

1 reference

12 December 2020

Zonal location of compensatory hepatocyte proliferation following chemically induced hepatotoxicity in rats and humans

1 reference

12 December 2020

Generation of hepatocytes from oval cell precursors in culture.

1 reference

12 December 2020

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome

1 reference

12 December 2020

The canals of Hering and hepatic stem cells in humans

1 reference

12 December 2020

The role of Kupffer cells in liver regeneration

1 reference

12 December 2020

Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.

1 reference

12 December 2020

Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice

1 reference

12 December 2020

Oncostatin M and hepatocyte growth factor induce hepatic maturation via distinct signaling pathways

1 reference

12 December 2020

Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration

1 reference

12 December 2020

Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes

1 reference

12 December 2020

Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes

1 reference

12 December 2020

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

1 reference

12 December 2020

HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures

1 reference

12 December 2020

The origin and liver repopulating capacity of murine oval cells

1 reference

12 December 2020

Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells

1 reference

12 December 2020

Subdivision of hexagonal liver lobules into a structural and functional unit; role in hepatic physiology and pathology

1 reference

12 December 2020

"Lifespan" of liver cells. Autoradio-graphic study using tritiated thymidine in normal, cirrhotic, and partially hepatectomized rats

1 reference

12 December 2020

Progenitor cells in diseased human liver

1 reference

12 December 2020

Canals of Hering: recent insights and current knowledge

1 reference

12 December 2020

Fibroblast growth factor enriches the embryonic liver cultures for hepatic progenitors

1 reference

12 December 2020

Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers.

1 reference

12 December 2020

Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice

1 reference

12 December 2020

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

1 reference

12 December 2020

Relation between hepatocyte G1 arrest, impaired hepatic regeneration, and fibrosis in chronic hepatitis C virus infection

1 reference

12 December 2020

Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice.

1 reference

12 December 2020

TWEAK induces liver progenitor cell proliferation

1 reference

12 December 2020

Cholangiocyte biology

1 reference

12 December 2020

Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice

1 reference

12 December 2020

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

1 reference

12 December 2020

Liver stem cells and their implication in hepatocellular and cholangiocarcinoma

1 reference

12 December 2020

Conditional deletion of beta-catenin reveals its role in liver growth and regeneration

1 reference

12 December 2020

Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice.

1 reference

12 December 2020

BMP-7 functions as a novel hormone to facilitate liver regeneration

1 reference

12 December 2020

Integrin-linked kinase is involved in matrix-induced hepatocyte differentiation

1 reference

12 December 2020

1 reference

12 December 2020

Interferon-gamma exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury

1 reference

12 December 2020

Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies

1 reference

12 December 2020

Endocrine and paracrine role of bile acids

1 reference

12 December 2020

Stem cells and liver regeneration.

1 reference

12 December 2020

Targeting liver fibrosis: strategies for development and validation of antifibrotic therapies.

1 reference

12 December 2020

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

1 reference

12 December 2020

Transcription dynamics in a physiological process: β-catenin signaling directs liver metabolic zonation

1 reference

12 December 2020

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

1 reference

12 December 2020

The histogenesis of regenerative nodules in human liver cirrhosis

1 reference

12 December 2020

FXR regulates liver repair after CCl4-induced toxic injury

1 reference

12 December 2020

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

1 reference

12 December 2020

Hedgehog signaling in the liver

1 reference

12 December 2020

New concepts in liver regeneration

1 reference

12 December 2020

FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways

1 reference

12 December 2020

Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells.

1 reference

12 December 2020

Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury

1 reference

12 December 2020

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

1 reference

12 December 2020

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

1 reference

12 December 2020

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.

1 reference

12 December 2020

Liver sinusoidal endothelial cell progenitor cells promote liver regeneration in rats

1 reference

12 December 2020

Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration.

1 reference

12 December 2020

Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice

1 reference

12 December 2020

Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice.

1 reference

12 December 2020

FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration

1 reference

12 December 2020

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

1 reference

12 December 2020

Robust cellular reprogramming occurs spontaneously during liver regeneration.

1 reference

12 December 2020

The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice

1 reference

12 December 2020

1 reference

12 December 2020

Polyploidization in liver tissue.

1 reference

12 December 2020

Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration.

1 reference

12 December 2020

Hepatocytes, rather than cholangiocytes, can be the major source of primitive ductules in the chronically injured mouse liver

1 reference

12 December 2020

The biliary epithelium gives rise to liver progenitor cells

1 reference

12 December 2020

Hippo pathway activity influences liver cell fate

1 reference

12 December 2020

How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis.

1 reference

12 December 2020

Adult hepatocytes are generated by self-duplication rather than stem cell differentiation.

1 reference

12 December 2020

Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury

1 reference

12 December 2020

Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury

1 reference

12 December 2020

Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes

1 reference

12 December 2020

Long-term culture of genome-stable bipotent stem cells from adult human liver

1 reference

12 December 2020

Lineage fate of ductular reactions in liver injury and carcinogenesis

1 reference

12 December 2020

Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse

1 reference

12 December 2020

The Bile Acid Receptor TGR5 and Liver Regeneration

1 reference

12 December 2020

Hepatic progenitor cells of biliary origin with liver repopulation capacity

1 reference

12 December 2020

Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver

1 reference

12 December 2020

Implications of microbiota and bile acid in liver injury and regeneration

1 reference

12 December 2020

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

1 reference

12 December 2020

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.

1 reference

12 December 2020

Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis.

1 reference

12 December 2020

Functional analysis of the relationship between intestinal microbiota and the expression of hepatic genes and pathways during the course of liver regeneration

1 reference

12 December 2020

Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease

1 reference

12 December 2020

Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy.

1 reference

12 December 2020

Hedgehog regulates yes-associated protein 1 in regenerating mouse liver

1 reference

12 December 2020

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

1 reference

12 December 2020

Novel bile acid therapeutics for the treatment of chronic liver diseases

1 reference

12 December 2020

Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

1 reference

12 December 2020

Upstream regulators of hepatic Wnt/β-catenin activity control liver metabolic zonation, development, and regeneration

1 reference

12 December 2020

Cholangiocarcinoma, gone without the Wnt?

1 reference

12 December 2020

Perioperative hepatocyte growth factor (HGF) infusions improve hepatic regeneration following portal branch ligation (PBL) in rodents.

1 reference

12 December 2020

Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration

1 reference

12 December 2020

Hepatostat: Liver regeneration and normal liver tissue maintenance

1 reference

12 December 2020

Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

1 reference

12 December 2020

Liver macrophages in tissue homeostasis and disease

1 reference

12 December 2020

Mechanisms of hepatic stellate cell activation

1 reference

12 December 2020

Update on the Mechanisms of Liver Regeneration

1 reference

12 December 2020

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.

1 reference

12 December 2020

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease.

1 reference

12 December 2020

Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury.

1 reference

12 December 2020

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.

1 reference

12 December 2020

A pivotal role of BEX1 in liver progenitor cell expansion in mice.

1 reference

12 December 2020

Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes

1 reference

12 December 2020

Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS19124115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30567401%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

30567401

1 reference