Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum (Q28649962)

25 June 2017

title

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum (English)

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calcium-dependent protein kinase 5

25 June 2017

main subject

Plasmodium falciparum

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1 reference

11 September 2018

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27

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Grennady Wirjanata

11

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Jutta Marfurt

10

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Iñigo Angulo-Barturen

18

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Thomas D Otto

6

Thomas D Otto

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Kiaran Kirk

Kiaran Kirk

26

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Vicky M. Avery

Vicky M Avery

23

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Susan A. Charman

Susan A Charman

17

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Natalie J Spillman

Natalie J Spillman

7

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Andrea Ruecker

Andrea Ruecker

24

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Michael Delves

Michael Delves

25

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Matthew Berriman

27

Matthew Berriman

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29

Jeremy Burrows

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25 June 2017

Akhil B Vaidya

1

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Joanne M Morrisey

2

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25 June 2017

Zhongsheng Zhang

3

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Sudipta Das

4

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Thomas M Daly

5

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Matthew Wyvratt

8

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25 June 2017

Peter Siegl

9

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Boni F Sebayang

12

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Ric N Price

13

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Arnab Chatterjee

14

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Advait Nagle

15

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Marcin Stasiak

16

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25 June 2017

Santiago Ferrer

19

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María Belén Jiménez-Díaz

20

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25 June 2017

María Santos Martínez

21

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Francisco Javier Gamo

22

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Sandhya Kortagere

28

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25 June 2017

Erkang Fan

30

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25 June 2017

Lawrence W Bergman

31

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25 June 2017

language of work or name

English

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publication date

25 November 2014

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25 June 2017

published in

Nature Communications

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25 June 2017

volume

5

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25 June 2017

page(s)

5521

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Creative Commons Attribution 4.0 International

25 June 2017

copyright license

start time

25 November 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4263321/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Ion and nutrient uptake by malaria parasite-infected erythrocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Spiroindolones, a potent compound class for the treatment of malaria

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Estimating the global clinical burden of Plasmodium falciparum malaria in 2007

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Artemisinin Resistance in Plasmodium falciparum Malaria

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Animal models of efficacy to accelerate drug discovery in malaria

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Malaria parasites tolerate a broad range of ionic environments and do not require host cation remodelling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

The state of the art in anti-malarial drug discovery and development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Development and host cell modifications of Plasmodium falciparum blood stages in four dimensions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Artemisinin resistance--the clock is ticking

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Sodium or potassium efflux ATPase a fungal, bryophyte, and protozoal ATPase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Artemisinin-based combination treatment of falciparum malaria.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Artemisinin-based combinations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Chloroquine-resistant malaria

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Perturbation of the pump-leak balance for Na(+) and K(+) in malaria-infected erythrocytes.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Membrane transport in the malaria-infected erythrocyte

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Variations in frequencies of drug resistance in Plasmodium falciparum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

Artemisinin resistance on the Thai-Cambodian border

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS6521

Analysis of a cation-transporting ATPase of Plasmodium falciparum

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS6521

Na+ extrusion imposes an acid load on the intraerythrocytic malaria parasite

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS6521

21 January 2018

Identifiers

DOI

10.1038/NCOMMS6521

1 reference

Dimensions Publication ID

25 June 2017

0 references

1008614784

0 references

OpenCitations bibliographic resource ID

202702

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

202702

1 reference