Abdulaziz Al Sheikh is a member of the [[Al ash-Sheikh]] family. In 1969-70 he assumed leadership at the Sheikh Muhammad Bin Ibrahim Mosque in Dukhna, Riyadh. In 1979 he was appointed assistant professor at the [[College of Sharia]], [[Mecca]].
In June 1999, [[King Fahd]] appointed Al Sheikh as [[Grand Mufti of SaudSaudi Arabia]], following the death of Grand Mufti [[Abdulaziz Bin Baz]].<ref name="Eur2002">{{cite book|author=Eur|title=The Middle East and North Africa 2003|url=https://books.google.com/books?id=4CfBKvsiWeQC&pg=PA949|access-date=1 September 2012|date=22 November 2002|publisher=Taylor & Francis|isbn=978-1-85743-132-2|pages=950|archive-date=23 June 2013|archive-url=https://web.archive.org/web/20130623194023/http://books.google.com/books?id=4CfBKvsiWeQC&pg=PA949|url-status=live}}</ref>