Bunyavirales: Difference between revisions

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* [[Lassa fever]] and [[Argentine hemorrhagic fever]] (reservoir: rodents; vector: aerosolized excreta from these mammals; family: Arenaviridae).
 
Bunyaviruses have segmented genomes, making them capable of rapid recombinationreassortment and increasing the risk of outbreak.<ref>{{Cite| doi = 10.1016/j.virol.2013.07.030| title = Viruses of the family Bunyaviridae: Are all available isolates reassortants?| date = November 2013}}</ref><ref>{{Cite journal| doi = 10.3390/v6114373| issn = 1999-4915| volume = 6| issue = 11| pages = 4373–4397| last1 = Horne| first1 = Kate McElroy| last2 = Vanlandingham| first2 = Dana L.| title = Bunyavirus-Vector Interactions| journal = Viruses| date = 2014-11-13| pmid = 25402172| pmc = 4246228| doi-access = free}}</ref> The bunyavirus that causes [[severe fever with thrombocytopenia syndrome]] can undergo recombination both by reassortment of [[genome]] segments and by intragenic [[homologous recombination]].<ref>Lv Q, Zhang H, Tian L, Zhang R, Zhang Z, Li J, Tong Y, Fan H, Carr MJ, Shi W. Novel sub-lineages, recombinants and reassortants of severe fever with thrombocytopenia syndrome virus. Ticks Tick Borne Dis. 2017 Mar;8(3):385-390. doi: 10.1016/j.ttbdis.2016.12.015. Epub 2017 Jan 3. {{PMID|28117273}}</ref><ref>He CQ, Ding NZ. Discovery of severe fever with thrombocytopenia syndrome bunyavirus strains originating from intragenic recombination. J Virol. 2012 Nov;86(22):12426-30. doi: 10.1128/JVI.01317-12. Epub 2012 Aug 29. {{PMID|22933273}}</ref> Bunyaviridae are transmitted by hematophagous arthropods including mosquitoes, midges, flies, and ticks. The viral incubation period is about 48 hours. Symptomatic infection typically causes non-specific [[flu-like]] symptoms with fever lasting for about three days. Because of their [[non-specific symptoms]], Bunyavirus infections are frequently mistaken for other illnesses. For example, Bwamba fever is often mistaken for malaria.<ref>{{Cite book| edition = 6| publisher = Mosby| isbn = 9780323054706| author = Patrick R. Murray, Ken S. Rosenthal and Michael A. Pfaller|title = Medical Microbiology, 6e| location = Philadelphia| date = 2008-12-24}}</ref>
 
==Prevention==