Portnoy married Renee Satherthwaite in 2009,{{cn|date=September 2022}} and the two separated in January 2017.<ref>{{cite web|title=El Pres State of the Union|url=https://www.barstoolsports.com/boston/el-pres-state-of-the-union/|website=Barstool Sports|date=2017-01-24}}</ref> In 2020, Portnoy donated $500,000 to The Barstool Fund, a relief effort for small business affected by the [[COVID-19 pandemic]].<ref>{{Cite web|title=Barstool Sports founder Dave Portnoy kickstarts fundraiser for small businesses affected by COVID-19|url=https://www.phillyvoice.com/barstool-sports-founder-dave-portnoy-fundraises-500000-small-businesses/|url-status=live|access-date=2021-03-05|website=www.phillyvoice.com|date=December 19, 2020|archive-url=https://web.archive.org/web/20201219151835/https://www.phillyvoice.com/barstool-sports-founder-dave-portnoy-fundraises-500000-small-businesses/ |archive-date=December 19, 2020 }}</ref><ref>{{Cite web|date=2021-01-06|title=Love Him Or Hate Him, Dave Portnoy Is Saving American Small Business With The Barstool Fund|url=https://sportshandle.com/dave-portnoy-raising-money/|access-date=2021-03-05|website=SportsHandle|language=en-US}}</ref> The campaign raised over $39 million for 348 businesses as of May 2021.<ref>{{Cite web|last=Conklin|first=Audrey|date=2020-12-23|title=Barstool's Dave Portnoy raises nearly $30M for 167 small businesses — and counting|url=https://www.foxbusiness.com/economy/barstools-dave-portnoy-millions-small-business-fund|access-date=2021-03-25|website=FOXBusiness|language=en-US}}</ref>