General anaesthesia: Difference between revisions

In the 1990s, a novel method of maintaining anaesthesia was developed in [[Glasgow]], Scotland. Called [[target controlled infusion]] (TCI), it involves using a computer-controlled syringe driver (pump) to infuse propofol throughout the duration of surgery, removing the need for a volatile anaesthetic and allowing pharmacologic principles to more precisely guide the amount of the drug used by setting the desired drug concentration. Advantages include faster recovery from anaesthesia, reduced incidence of postoperative nausea and vomiting, and absence of a trigger for [[malignant hyperthermia]]. At present, TCI is not permitted in the United States, but a syringe pump delivering a specific rate of medication is commonly used instead.<ref>{{Cite journal |last1=Absalom |first1=Anthony R. |last2=Glen |first2=John Iain B. |last3=Zwart |first3=Gerrit J. C. |last4=Schnider |first4=Thomas W. |last5=Struys |first5=Michel M. R. F. |date=January 2016 |title=Target-Controlled Infusion: A Mature Technology |url=https://pubmed.ncbi.nlm.nih.gov/26516798 |journal=Anesthesia and Analgesia |volume=122 |issue=1 |pages=70–78 |doi=10.1213/ANE.0000000000001009 |issn=1526-7598 |pmid=26516798|s2cid=41023659 |doi-access=free }}</ref>