On September 19, 2019, [[CBS]] put ''Good Sam'', a family medical drama from writer Katie Wech, who will produce the series with Jennie Snyder Urman through her Sutton St. Productions and CBS Television Studios into development.<ref>{{cite web|first=Denise|last=Petski|title=CBS Buys Family Medical Drama 'Good Sam' From Katie Wech & Jennie Snyder Urman|url=https://deadline.com/2019/09/cbs-buys-medical-drama-good-sam-katie-wech-jennie-snyder-urman-1202739128/|date=September 19, 2019|website=[[Deadline Hollywood]]|access-date=June 27, 2020|archive-date=December 6, 2019|archive-url=https://web.archive.org/web/20191206134904/https://deadline.com/2019/09/cbs-buys-medical-drama-good-sam-katie-wech-jennie-snyder-urman-1202739128/|url-status=live}}</ref> In February 2020, the series was given a pilot order.<ref>{{cite web|first=Denise|last=Petski|title=CBS Orders Drama Pilots 'Good Sam' From Katie Wech & 'Out The Door' From Evan Katz|url=https://deadline.com/2020/02/cbs-orders-drama-pilots-good-sam-katie-wech-out-the-door-evan-katz-1202854279/|date=February 7, 2020|website=[[Deadline Hollywood]]|access-date=June 27, 2020|archive-date=June 20, 2020|archive-url=https://web.archive.org/web/20200620165433/https://deadline.com/2020/02/cbs-orders-drama-pilots-good-sam-katie-wech-out-the-door-evan-katz-1202854279/|url-status=live}}</ref> In February 2020, [[Sophia Bush]] was cast as Sam Griffith.<ref>{{cite web|first=Nellie|last=Andreeva|title=Sophia Bush To Star In CBS Drama Pilot 'Good Sam'|url=https://deadline.com/2020/02/sophia-bush-star-cbs-drama-pilot-good-sam-1202870664/|date=February 28, 2020|website=[[Deadline Hollywood]]|access-date=June 27, 2020|archive-date=June 8, 2020|archive-url=https://web.archive.org/web/20200608142818/https://deadline.com/2020/02/sophia-bush-star-cbs-drama-pilot-good-sam-1202870664/|url-status=live}}</ref> In March 2020, [[Jason Isaacs]] joined the cast as Sam's boss, Dr. Paul "Griff" Griffith.<ref>{{cite web|first=Nellie|last=Andreeva|title=Jason Isaacs To Star In CBS Drama Pilot 'Good Sam'|url=https://deadline.com/2020/03/jason-isaacs-star-icbs-drama-pilot-good-sam-1202872378/|date=March 2, 2020|website=[[Deadline Hollywood]]|access-date=June 27, 2020|archive-date=June 6, 2020|archive-url=https://web.archive.org/web/20200606205658/https://deadline.com/2020/03/jason-isaacs-star-icbs-drama-pilot-good-sam-1202872378/|url-status=live}}</ref> On May 14, 2021, the show was given a series order.<ref name="SeriesOrder">{{cite web|url=https://deadline.com/2021/05/sophia-bushs-good-sam-pete-holmes-smallwood-picked-up-to-series-cbs-1234757238/|title=Sophia Bush's 'Good Sam' & Pete Holmes' 'Smallwood' Picked Up To Series At CBS|work=[[Deadline Hollywood]]|date=May 14, 2021|access-date=May 20, 2021|last=White|first=Peter}}</ref>