Polyhalogenated compound: Difference between revisions

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A '''Polyhalogenatedpolyhalogenated compoundscompound''' ('''PHC's'') areis any compoundscompound with multiple substitutions of halogens[[halogen]]s. They are of particular interest and importance because [[halogens]] generally are highly reactive and alsothey [[bioaccumulate]] in humans, and comprise a superset of which has many toxic and carcinogenic industrial chemicals as members. [[Polybrominated diphenyl ethers|PBDE]]'s, [[Polychlorinated biphenyl|PCB]]'s, [[DioxinsPolychlorinated dibenzodioxins|dioxins (PCDDs)]] and [[Perfluorinated compounds|PFC]]'s are all polyhalogenated compounds. They are generally non-[[miscible]] in organic solvents or water, but miscible in some [[hydrocarbons]] from which they often derive.
 
==Uses==
PHC'sPHCs are used in a vast array of manufactured products, from wood treatments, to cookware coatings, to non-stick, waterproof, and fire-resistant coatings, cosmetics, medicine, electronic fluids, food containers, and wrappings, in everything from [[furniture]] and furnishings, [[automobiles]], [[airplanes]], [[plastics]], [[clothing]] and cloth, surgery, insulation, adhesives, paints, sealants, lubricating oils, polyurethane foams, cancer therapy, and medical imaging. They are also heavily used in [[pest control]].
 
==Safety==
PHC'sPHCs include notoriously dangerous substances, including [[Agent Orange]], [[DDT]], and other [[pesticides]]. Many non-pesticide PHC'sPHCs have the same safety issues as pesticides.
 
==Types==
* Polycholorinated, e.g. [[Polychlorinated biphenyl|PCB]]'s, [[Dioxinspolychlorinated dibenzodioxins|dioxins]] (PCDDs), [[Hexachlorophenehexachlorophene]], [[Dibenzofuransdibenzofurans]] (PCDFs), [[polychloro phenoxy phenol]]s (PCPPs), [[polychlorinated diphenyl ethers]] (PCDEs).
* Polybrominated, e.g., [[PBDE]]'s, [[polybrominated biphenyls]] (PBBs).
* [[PerflourinatedPerfluorinated compounds]]
* Polyiodinated compounds
 
==Breakdown of Compoundscompounds==
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Despite bioaccumulating in humans, it has been claimed that a method during manufacture using anaerobic bacteria may be efficacious <ref>{{Cite journal |doi = 10.1038/368627a0|pmid = 8145847|title = Metabolism of polyhalogenated compounds by a genetically engineered bacterium|journal = Nature|volume = 368|issue = 6472|pages = 627–629|year = 1994|last1 = Wackett|first1 = Lawrence P.|last2 = Sadowsky|first2 = Michael J.|last3 = Newman|first3 = Lisa M.|last4 = Hur|first4 = Hor-Gil|last5 = Li|first5 = Shuying|bibcode = 1994Natur.368..627W|s2cid = 4315658}}</ref>
 
==Breakdown of Compounds==
Despite bioaccumulating in humans, patents have been filed for removal of halogen by electrolysis<ref>[http://www.patentstorm.us/patents/4585533/description.html US Patent 4585533 - Removal of halogen from polyhalogenated compounds by electrolysis]</ref> during manufacturing, though toxic chlorinated compounds may be created as byproducts of chlorinated compounds. Another method during manufacture is to use anaerobic bacteria <ref>[http://www.nature.com/nature/journal/v368/n6472/abs/368627a0.html Metabolism of polyhalogenated compounds by a genetically engineered bacterium]</ref>
 
==References==
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{{HealthIssuesOfPlastics}}
 
[[Category:Persistent organic pollutantsOrganohalides]]
 
 
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