Content deleted Content added
fixed sentence |
m minor grammar fix |
||
Line 1:
'''Respiratory compensation''' is the modulation by the [[respiratory center|brainstem respiratory centers]], which involve altering [[alveolar ventilation]] to try and bring the plasma [[pH]] back to its normal value (7.4) in order to keep the [[Acid–base homeostasis|acid-base balance]] in the body. It usually occurs within minutes to hours and is much faster than [[renal compensation]] (which takes several days), but has less ability to restore normal values.
In [[metabolic acidosis]], [[chemoreceptors]] sense a deranged [[Acid–base homeostasis|acid-base balance]] with a plasma [[pH]] of less than normal (<7.4). The chemoreceptors send afferent fibers to the brainstem respiratory centers. The [[Respiratory center|brainstem respiratory centers]] increase alveolar ventilation ([[hyperventilation]]) so that [[carbon dioxide]] (CO2) can be breathed off, resulting in an increase of plasma pH.<ref>https://www.ncbi.nlm.nih.gov/books/NBK507807/</ref> The amount of respiratory compensation in metabolic acidosis can be estimated using [[Winters' formula]].
| |||