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In [[metabolic alkalosis]], [[chemoreceptors]] sense a deranged [[Acid–base homeostasis|acid-base balance]] with a plasma [[pH]] of more than normal (>7.4). The chemoreceptors send afferent fibers to the brainstem respiratory centers. The [[Respiratory center|brainstem respiratory centers]] decrease alveolar ventilation ([[hypoventilation]]) to create a rise in arterial [[carbon dioxide]] (CO2) tension, resulting in a decrease of plasma pH.<ref>https://www.ncbi.nlm.nih.gov/books/NBK507807/</ref>
The [[Respiratory center|respiratory brainstem centers]] can only compensate for metabolic acid-base disturbances. Renal compensation is needed to balance respiratory acid-base syndromes. The kidneys can compensate for both, respiratory and metabolic acid-base imbalances.
==References==
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