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Research published in 2020 shows that tardigrades are sensitive to high temperatures. Researchers showed it takes 48 hours at {{Cvt|37.1|C|F|abbr=}} to kill half of active tardigrades that have not been acclimated to heat. Acclimation boosted the temperature needed to kill half of active tardigrades to {{Cvt|37.6|C|F|abbr=}}. Tardigrades in the tun state fared a bit better, tolerating higher temperatures. It took heating to {{Cvt|82.7|C|F|abbr=}} to kill half of tun-state tardigrades within one hour. Longer exposure time decreased the temperature needed for lethality, though. For 24 hours of exposure, {{Cvt|63.1|C|F|abbr=}} was enough to kill half of the tun-state tardigrades.<ref>{{cite journal |last1=Neves |first1=Ricardo Cardoso |last2=Hvidepil |first2=Lykke K. B. |last3=Sørensen-Hygum |first3=Thomas L. |last4=Stuart |first4=Robyn M. |last5=Møbjerg |first5=Nadja |title=Thermotolerance experiments on active and desiccated states of Ramazzottius varieornatus emphasize that tardigrades are sensitive to high temperatures |journal=Scientific Reports |date=9 January 2020 |volume=10 |issue=1 |page=94 |doi=10.1038/s41598-019-56965-z |pmid=31919388 |pmc=6952461 |bibcode=2020NatSR..10...94N }}</ref>
In 2021 scientists reported they had cooled down a tardigrade of the species Ramazzottius varieornatus to 10 millikelvin above absolute zero, and put it under extremely low pressure of 0.000006 millibars. After 420 hours, the animal was brought back to life again.<ref>[https://www.sciencealert.com/physicists-claim-they-ve-entangled-a-tardigrade-with-qubits-but-did-they Physicists Claim They've Quantum Entangled a Tardigrade With a Qubit. But Have They?]</ref>
* [[Pressure]] – they can withstand the extremely low pressure of a [[vacuum]] and also very high pressures, more than 1,200 times [[atmospheric pressure]]. Some species can also withstand pressures of 6,000 atmospheres, which is nearly six times the pressure of water in the deepest ocean trench, the [[Mariana Trench]].<ref name="Seki98">{{cite journal |doi=10.1038/27576 |title=Preserving tardigrades under pressure |journal=Nature |volume=395 |issue=6705 |pages=853–54 |year=1998 |last1=Seki |first1=Kunihiro |last2=Toyoshima |first2=Masato |bibcode=1998Natur.395..853S |s2cid=4429569 }}</ref> Tardigrades can survive at altitudes of more than {{convert|19,600|ft|m|abbr=off|sp=us}} and depths of more than {{convert|15,000|ft|m}} below the surface.<ref>{{Cite web |last1=Weisberger |first1=Mindy |last2=Bradford |first2=Alina |date=2021-11-12 |title=What are tardigrades and why are they nearly indestructible? |url=https://www.livescience.com/57985-tardigrade-facts.html |access-date=2024-06-13 |website=livescience.com |language=en}}</ref>
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