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*1918: Oxygen masks are used to treat combat-induced [[pulmonary edema]].<ref name="Ward1997">Ward JJ, Helmholtz HF: Roots of the respiratory care profession. In Burton GG, Hodgkin JE, Ward JJ, editors: Respiratory care: a guide to clinical practice, ed 4, Philadelphia, 1997, Lippincott.</ref>
*1928: Phillip Drinker develops the "[[iron lung]]" negative pressure ventilator.<ref name="Ward1997"/>
*1935: Carl Matthes invented the first noninvasive oximeter employing an ear probe<ref name="pmid3537215">{{cite journal| author=Severinghaus JW, Astrup PB| title=History of blood gas analysis. VI. Oximetry. | journal=J Clin Monit | year= 1986 | volume= 2 | issue= 4 | pages= 270-88 | pmid=3537215 | doi= | pmc= | url= }} </ref>.
*1943: [[Dr. Edwin R. Levine, MD]] began training technicians in basic inhalation therapy for post-surgical patients.
*1946: Dr Levine and his technicians formed the [[Inhalation Therapy Association]].
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