Tonofibril: Difference between revisions

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{{short description|Protein cytoskeletal component}}
<!-- Deleted image removed: [[File:Tonofibril and Desmosome.jpg|thumb|<ref>{{Cite web|title = Epidermis - Derm101|url = http://www.derm101.com/inflammatory/embryologic-histologic-and-anatomic-aspects/epidermis/|website = www.derm101.com|accessdate = 2015-11-23}}</ref> Loops of tonofibrils at a desmosome.]] -->
'''Tonofibrils''' are cytoplasmic protein structures in [[epithelial]] tissues that converge at [[desmosomes]] and [[hemidesmosomes]].<ref name=":0">{{DorlandsDict|eight/000109361|tonofibril}}</ref> They consist of fine [[fibril]]s in epithelial cells that are anchored to the [[cytoskeleton]].<ref name=":1" /> They were discovered by [[Rudolf Heidenhain]], and first described in detail by [[Louis-Antoine Ranvier]] in 1897.<ref>{{Cite journal|last1=Charles|first1=Arwyn|last2=Smiddy|first2=F. G.|date=1957-09-01|title=The Tonofibrils of the Human Epidermis1|journal=Journal of Investigative Dermatology|volume=29|issue=5|pages=327–338|doi=10.1038/jid.1957.108|pmid=13502588|issn=0022-202X|doi-access=free}}</ref>