Ventricular outflow tract obstruction: Difference between revisions

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* [[Coarctation of the aorta]]
* [[Hypoplastic left heart syndrome]]
 
==Pathophysiology==
A ventricular outflow tract obstruction means there is a limitation in the blood flow out of either the right or left ventricles of the heart, depending on where the obstruction is. This can lead to [[cardiac hypertrophy]], [[dilatation]] of the heart, and ultimately [[heart failure]] in some cases.<ref name="NCBI LVOT">{{cite web |last1=Vilcant |first1=Viliane |last2=Hai |first2=Ofek |title=Left Ventricular Outflow Tract Obstruction |url=https://www.ncbi.nlm.nih.gov/books/NBK470446/#:~:text=Introduction,LV)%20outflow%20to%20descending%20aorta. |website=StatPearls |publisher=StatPearls Publishing |date=2022}}</ref> The right side of the heart is much smaller and weaker than the left side of the heart. It pumps de-oxygenated blood into the lungs. The left side of the heart is more muscular than the right side of the heart. It pumps oxygenated blood from the lungs into the aorta to perfuse the rest of the body.<ref>{{cite web |title=Normal Heart |url=https://myhealth.alberta.ca/Health/Pages/conditions.aspx?hwid=aa54865#:~:text=The%20right%20side%20of%20your,the%20rest%20of%20your%20body. |website=myhealth.alberta.ca}}</ref> When the heart has to pump against increased resistance, or [[afterload]], as in the case of a ventricular obstruction, it compensates by growing in size. This adaptation is beneficial to pump blood past the obstruction, but eventually this hypertrophy can lead to other problems including arrhythmias, ischemia, and heart failure.<ref name="Samak cardiac hypertrophy">{{cite journal |last1=Samak |first1=M |last2=Fatullayev |first2=J |last3=Sabashnikov |first3=A |last4=Zeriouh |first4=M |last5=Schmack |first5=B |last6=Farag |first6=M |last7=Popov |first7=AF |last8=Dohmen |first8=PM |last9=Choi |first9=YH |last10=Wahlers |first10=T |last11=Weymann |first11=A |title=Cardiac Hypertrophy: An Introduction to Molecular and Cellular Basis. |journal=Medical science monitor basic research |date=23 July 2016 |volume=22 |pages=75-9 |doi=10.12659/MSMBR.900437 |pmid=27450399}}</ref>
 
 
==References==