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{{wikify|date=November 2007}} |
{{wikify|date=November 2007}} |
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'''Kexin''' is a prohormone processing protease found in the budding [[yeast]] ([[Saccharomyces cerevisiae]]) that shares similarities with [[subtilisin]] |
'''Kexin''' is a prohormone processing protease found in the budding [[yeast]] ([[Saccharomyces cerevisiae]]) that shares structural similarities with the bacterial protease [[subtilisin]] (1). It is encoded by the yeast gene KEX2 and usually referred to in the scientific community as Kex2p. The first mammalian homologue of this protein to be identified was [[furin]]. |
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'''References'''<br /> |
'''References'''<br /> |
Revision as of 19:17, 18 November 2007
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Kexin is a prohormone processing protease found in the budding yeast (Saccharomyces cerevisiae) that shares structural similarities with the bacterial protease subtilisin (1). It is encoded by the yeast gene KEX2 and usually referred to in the scientific community as Kex2p. The first mammalian homologue of this protein to be identified was furin.
References
(1) Rockwell, Nathan C.; Krysan, Damian J.; Komiyama, Tomoko; Fuller, Robert S. (2002) "Precursor processing by Kex2/furin proteases" Chem. Rev. 102: 4525-4548.