IL17RD: Difference between revisions
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==Function== |
==Function== |
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This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. |
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the [[interleukin-17 receptor signaling complex]], and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects [[fibroblast growth factor]] signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. |
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== References == |
== References == |
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Revision as of 21:56, 18 February 2017
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | IL17RD, HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 606807; MGI: 2159727; HomoloGene: 9717; GeneCards: IL17RD; OMA:IL17RD - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Interleukin 17 receptor D is a protein that in humans is encoded by the IL17RD gene. [5]
Function
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000144730 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040717 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Interleukin 17 receptor D". Retrieved 2016-04-17.
Further reading
- Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R (2003). "Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation". J. Biol. Chem. 278 (16): 14087–91. doi:10.1074/jbc.C200606200. PMID 12604616.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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