Talk:Amlodipine

Question on external links

Hi, I wanted to understand why in external links we can see the manufacturer site and it is not allowed to see an exclusive and informative site about the product like Amlodipine.com. Thanks (Rmrr (talk) 11:07, 20 June 2008 (UTC))

No response from User:CliffC? --99.145.131.169 (talk) 15:06, 9 October 2008 (UTC)

CliffC and several other editors responded on Rmrr's talk page here in June. In summary, they told him to stop trying to advertise on Wikipedia and directed him to WP:EL and WP:ADVERT. --CliffC (talk) 21:43, 9 October 2008 (UTC)

Categories

I do not think, that it is necessary to place this article into "Pfizer" category. Actually, not all Amlodipine is Norvasc, there are many other variants of Amlodipine, created by many other pharmaceutical companies--Армонд^@ 17:49, 25 February 2009 (UTC)

A topic of...

Amlodipine Besylate has been added based on the following http://www.tga.gov.au/docs/pdf/aan/aanchem.pdf --222.64.18.236 (talk) 10:41, 21 June 2009 (UTC)

http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=A5605%7CSIGMA&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&F=SPEC --222.64.18.236 (talk) 10:43, 21 June 2009 (UTC)

Anyone hear of "amidoipine"?

I have come across this misspelling a few times in the medical field (I am a nursing student) and I wonder if anyone else has, or if anyone has any explanation as to where this jumbling comes from. Is it some type of alternative generic name (as budeprione is to bupropion [Wellbutrin])? Trust me, I have scoured the internet as well as the hospital's online medical library but not yet come across it, so I assume it's some kind of mistake, but would love to hear if there is some other explanation.Hagenb (talk) 00:09, 1 December 2009 (UTC)

Stereochemistry

Just wanted to note that I could not determine, looking at the IUPAC name and the image of the chemicals formula, I only saw 1 stereocenter, yet the IUPAC name shows 2; in addition, the stereocenter I thought I had picked out correctly didn't fit with any of the possible numbering schemes. Because chemistry is an important aspect of pharmaceutical articles and is all too often ignored, I'd really like to see something explaining this. If it weren't important, there wouldn't be the epithet of 'racemate;' methadone is a racemate, but its stereochemistry is not discussed very much because it's only available as racemate and studies with the pure isomers are few, due to the expense and relatively small benefit in isolating a racemate's constituents. Not like it'll happen before I die, in all seriousness; but hopefully this message might indirectly help a future visitor, if only a tiny bit. To recap: someone with the appropriate knowledge would be doing WP and its denizens a service to add even a little bit on that issue here. At the very least, it needs to be cleared up whether there are 1 or 2 stereocenters as well as which carbons they are located on; this could be done by modifying the image to show the resonance differently, or something.. I dunno. Too many words already for something that might never be read. Mr0t1633 (talk) 20:13, 10 December 2009 (UTC)

Moin, moin, Mr0t1633, I agree 100%. The practical importance of stereochemistry is presently underestimated at Wikipedia quite ofton. The different biological/pharmacological behavior of enantiomers is obvious/normal/a rule. Best regards, --Jü (talk) 22:16, 10 December 2009 (UTC)

Copyright violation !!

See please http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=22972 "Mechanism of Action" and more Nini00 (talk) 20:03, 8 December 2012 (UTC)

Can the article be updated if cross-reactions with grapefruit-juice are credible?

I'm not qualified to judge what is said here: http://www.cmaj.ca/content/suppl/2012/11/26/cmaj.120951.DC1/grape-bailey-1-at.pdf and http://well.blogs.nytimes.com/2012/12/17/grapefruit-is-a-culprit-in-more-drug-reactions/ but if the above are credible can someone update this Wikipedia article with this information?76.8.67.2 (talk) 09:05, 6 January 2013 (UTC)Christopher L. Simpson

Done! Ashleyleia (talk) 15:48, 24 March 2013 (UTC)

Clarification of elimination from the body

In the interactions section, CYP3A4 as the pathway for metabolization, but in Pharmacokinetics and metabolism section, it's mentioned that 60% of the drug is recovered in the urine. Is elimination from the body primarily liver driven or renal driven?Wzrd1 (talk) 00:49, 6 July 2013 (UTC)